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sodium monofluorophosphate : ウィキペディア英語版
sodium monofluorophosphate

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Sodium monofluorophosphate, commonly abbreviated MFP, is an inorganic compound with the chemical formula Na2PO3F. Typical for a salt, MFP is odourless, colourless, and water-soluble. This salt is an ingredient in some toothpastes.〔Klaus Schrödter, Gerhard Bettermann, Thomas Staffel, Friedrich Wahl, Thomas Klein, Thomas Hofmann "Phosphoric Acid and Phosphates" in ''Ullmann’s Encyclopedia of Industrial Chemistry'' 2008, Wiley-VCH, Weinheim. 〕
==Uses of MFP==
MFP is best known as an ingredient in some toothpastes.〔Wolfgang Weinert "Oral Hygiene Products" in ''Ullmann’s Encyclopedia of Industrial Chemistry'' 2000, Wiley-VCH, Weinheim. 〕 It functions as a source of fluoride via the following hydrolysis reaction:〔
:PO3F2− + OH → HPO42− + F
Fluoride protects tooth enamel from attack by bacteria that cause dental caries (cavities). Although developed by a chemist at Procter and Gamble, its use in toothpaste (Colgate toothpaste) was patented by Colgate-Palmolive, as Procter and Gamble was engaged in the marketing of Crest toothpaste (containing stannous fluoride, marketed as "Fluoristan"). In the early 1980s, Crest was reformulated to use MFP, under the trademark "Fluoristat"; today Crest toothpastes use sodium fluoride.
MFP is also used in some medications for the treatment of osteoporosis.〔
In 1991, sodium monofluorophosphate was found by Calgon to inhibit the dissolution of lead in drinking water when used in concentrations between 0.1 mg/L and 500 mg/L.〔Peter Meiers (Monofluorophosphate History )〕

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